Description

Alpha GPC

• Purity Alpha GPC≥ 99%

• Net weight: 1gram

• Cas No. : 28319-77-9

• Molecular Formula: C8H20NO6P

• Molecular weight: 257.223 g-mol-1

• Use: Product for laboratory testing not for consumption.

What is Alpha GPC?

Alpha GPC, or alpha glycerylphosphorylcholine, is one form of choline (along with choline CDP). The compound is also referred to as choline alphoscerate, alpha-glycerophosphocholine, α-GPC, glycerol alphoscerate and (2S)-2,3-dihydroxypropyl-2-(trimethylaspartyl)ethyl phosphate. This form of choline occurs physiologically in the human body. It stands out for its excellent solubility in water. Unlike choline itself,lpha GPC penetrates the blood-brain barrier. And therefore it can be a carrier of choline to the central nervous system – the molecule of this compound contains more than 40% choline. The compound breaks down into choline and glycerophosphate. Both of these compounds are excellent at strengthening cell membranes and ensuring their integrity. In addition, choline is used in the synthesis of the neurotransmitter acetylcholine.

Application of Alpha GPC

Alpha glycylphosphorylcholine is a preparation used to improve cognitive function. It is ideal for people who need to improve their learning processes. The product facilitates the assimilation of information, improves memory. In addition, it supports
motivation
and willingness to take action.

The product can support the treatment of Alzheimer’s disease, a neurodegenerative disorder that progresses with cognitive impairment. Since the product helps increase the synthesis of growth hormone, it can be used in states of growth hormone deficiency. The effects of supplementation can be felt in both short-term and long-term use.

Mechanism of action

Alpha GPC is a carrier of choline, which is used as a precursor for the synthesis of acetylcholine. This neurotransmitter activates the cholinergic system, thus supporting cognitive function. Ingestion of α-GPC is accompanied by increased acetylcholine release in the brain’s hippocampus. Enhanced cholinergic neurotransmission was also observed.

The supportive effect of the product on the brain is also due to the improvement of cerebral circulation. By increasing blood pressure in the brain, there is better oxygenation and nourishment of brain cells.

Dosage of Alpha GPC

The daily dose of α-GPC is about 300 to 1,200 mg. Usually 400 mg is taken 2-3 times a day, between jobs. It is beneficial to combine this form of choline with uridine.

References:

1. https://pubchem.ncbi.nlm.nih.gov/compound/alpha-Glycerylphosphorylcholine
2. Tamura Y, Takata K, Matsubara K, Kataoka Y. Alpha-Glycerylphosphorylcholine Increases Motivation in Healthy Volunteers: A Single-Blind, Randomized, Placebo-Controlled Human Study. Nutrients. 2021 Jun 18;13(6):2091;
   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235064/
   
3. Parker AG, Byars A, Purpura M, Jäger R. The effects of alpha-glycerylphosphorylcholine, caffeine or placebo on markers of mood, cognitive function, power, speed, and agility. J Int Soc Sports Nutr. 2015 Sep 21;12(Suppl 1):P41;
   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595381/
   
4. Di Perri R, Coppola G, Ambrosio LA, Grasso A, Puca FM, Rizzo M. A multicentre trial to evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res. 1991 Jul-Aug;19(4):330-41;
   https://pubmed.ncbi.nlm.nih.gov/1916007/
   

Similar chemicals:

• 28319-77-9
• 248-962-2
• ALPHA-GLYCERYLPHOSPHORYLCHOLINE
• CHOLINE ALPHOSCERATE [INN]
• CHOLINE ALPHOSCERATE [MI]
• ETHANAMINIUM, 2-((((2R)-2,3-DIHYDROXYPROPOXXY)HYDROXYPHOSPHINYL)OXY)-N,N,N-TRIMETHYL-, INNER SALT
• CHOLINE ALPHOSCERATE [WHO-DD]
• CHOLINE ALPHOSCERATE
• CHOLINE ALPHOSCERATE [MART .]
• GLIATILIN
• CHOLINE HYDROXIDE, (R)-2,3-DIHYDROXYPROPYL HYDROGEN PHOSPHATE, INNER SALT
• GLYCEROPHOSPHOCHOLINE [INCI]
• GLYCEROPHOSPHOCHOLINE
• L-ALPHA-GLYCERYLPHOSPHORYLCHOLINE [USP-RS]
• L-.ALPHA.-GLYCERYLPHOSPHORYLCHOLINE