5-HTP, czystość ≥ 99.00% 1000mg

Description

5-HTP or 5-Hydroxytryptophan

Purity: ≥ 99.00%
Net Weight: 1000mg
Cas No.: 56-69-9
Molecular Formula: C11H12N2O3
Molar Mass: 220.23 g·mol−1
5-HTP, also known as 5-hydroxytryptophan, is a naturally occurring precursor to the neurotransmitter serotonin. In addition to its presence in the body, the primary source of 5-HTP is the seeds of the Griffonia simplicifolia plant.

Due to its potential ability to modulate serotonin levels in the brain, 5-HTP is often considered in the context of mood improvement, regulating sleep patterns, and appetite control. Studies suggest that it may influence various aspects of behavior and the functioning of the nervous system.

Caution should be exercised when using 5-HTP, especially in combination with drugs that affect the serotonin system, due to the potential risk of serotonin syndrome.

The product has undergone physicochemical tests and checks for the presence of heavy metals. It is packaged in aluminum sachets with drawstring closures.

Attention! 5-HTP is intended exclusively for laboratory research and should not be consumed in any form. This product is for laboratory research purposes only and is not for use on Homo sapiens.

For more information on 5-HTP, please refer to specialized publications and scientific literature. Below, you will find more detailed information.

Potential Risks

Serotonin Syndrome (SS)

Serotonin syndrome is a potentially life-threatening condition that occurs when the body has too much serotonin – a neurotransmitter responsible for regulating mood, behavior, body temperature, and other physiological functions. This syndrome is most commonly caused by the use of drugs that increase serotonin levels in the brain.

Symptoms of serotonin syndrome include:

Agitation or restlessness
Diarrhea
Tremors or seizures
Fever
Loss of motor coordination
Nausea and vomiting
Headache
Rapid heartbeat
Excessive sweating
Dilated pupils
Rhythmic muscle contractions
5-HTP and DMT

5-HTP (5-hydroxytryptophan) is a precursor to serotonin in the brain. DMT (dimethyltryptamine) is a psychedelic compound that interacts with many serotonin receptors in the brain. If 5-HTP is used in conjunction with DMT, there may be an excessive increase in serotonin levels, increasing the risk of serotonin syndrome.

Additionally, DMT interacts with serotonin 5-HT2A receptors, which play a crucial role in the mechanism of action of many psychedelics. If serotonin levels in the brain become too high (e.g., through 5-HTP supplementation), it can disrupt DMT’s interactions with these receptors and affect the psychedelic experience.

In summary, due to the risk of serotonin syndrome and potential disruption of DMT’s effects, combining 5-HTP with DMT is not recommended. If someone is considering using these substances simultaneously, they should consult a doctor.

Scientific References on 5-HTP

Birdsall, T. C. (1998). „5-Hydroxytryptophan: a clinically-effective serotonin precursor.” Alternative Medicine Review, 3(4), 271-280.
Caruso, I., Sarzi Puttini, P., Cazzola, M., & Azzolini, V. (1992). Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. Journal of International Medical Research, 20(2), 182-189.
Ceci, F., Cangiano, C., Cairella, M., Cascino, A., Del Ben, M., Muscaritoli, M., … & Rossi Fanelli, F. (1989). The effects of oral 5-hydroxytryptophan administration on feeding behavior in obese adult female subjects. Journal of neural transmission, 76(2), 109-117.
Shaw, K., Turner, J., & Del Mar, C. (2002). Tryptophan and 5‐hydroxytryptophan for depression. Cochrane Database of Systematic Reviews, (1).
Jangid, P., Malik, P., Singh, P., Sharma, M., & Gulia, A. K. (2013). Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode. Asian journal of psychiatry, 6(1), 29-34.
Magnussen, I., & Nielsen-Kudsk, F. (1980). Bioavailability and related pharmacokinetics in man of orally administered L-5-hydroxytryptophan in steady state. Acta pharmacologica et toxicologica, 46(4), 257-262.