AbbreviationsEuropejska umowa dot. międzynarodowego przewozu towarów niebezpiecznych, Oszacowanie toksyczności ostrej (Acute Toxicity Estimate), Chemical Abstracts Service, Classification, Labelling and Packaging (Rozp. 1272/2008), Rakotwórczość, mutagenność, toksyczność reprodukcyjna, Pochodny poziom niepowodujący zmian (Derived No-Effect Level), European Community number, Środki ochrony indywidualnej, Globalnie Zharmonizowany System (Globally Harmonized System), Międzynarodowe Zrzeszenie Transportu Lotniczego, Międzynarodowy kodeks morski towarów niebezpiecznych, Karta Charakterystyki (Safety Data Sheet), Stężenie śmiertelne 50% (Lethal Concentration), Dawka śmiertelna 50% (Lethal Dose), Najwyższe dopuszczalne stężenie (na stanowisku pracy), Chwilowe NDS, Occupational Exposure Limit, Trwałe, bioakumulacyjne i toksyczne, Przewidywane stężenie niepowodujące zmian (Predicted No-Effect Concentration), Registration, Evaluation, Authorisation and Restriction of Chemicals (Rozp. 1907/2006), Safety Data Sheet, Toksyczność narządowa (Specific Target Organ Toxicity), Substancja wzbudzająca szczególnie duże obawy (Substance of Very High Concern), Topological Polar Surface Area, Bardzo trwałe i bardzo bioakumulacyjne
Version historyv1, 27.09.2026, Pierwsza emisja. Auto-wygenerowane przez MOL-GOD v3.12.32.
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ReferencesPubChem, PubChem PUG REST API, https://pubchem.ncbi.nlm.nih.gov/compound/16050328, Cache+consensus, Local cache (previously fetched), Local Cache, Local cache (previously fetched), Wikidata, wikidata, Literature, literature
References chicago[1] PE i Rada. Rozp.(WE) nr 1907/2006 (REACH). Art.31, Zał.II. Dz.Urz.UE L 396/2006., [2] Komisja Europejska. Rozp.(UE) 2020/878 — zmiana Zał.II REACH. Dz.Urz.UE L 203/2020. Od 01.01.2023., [3] PE i Rada. Rozp.(WE) 1272/2008 (CLP)+ATP 19. Dz.Urz.UE L 353/2008., [4] United Nations. GHS Rev.9. ST/SG/AC.10/30/Rev.9. ONZ, 2021., [5] ISO. ISO 7010:2019 — Graphical symbols. Safety signs., [6] ISO. ISO 3864-1:2011 — Safety colours and safety signs., [7] PubChem. PubChem PUG REST API. URL: https://pubchem.ncbi.nlm.nih.gov/compound/16050328 Data: 2026-09-27., [8] Cache+consensus. Local cache (previously fetched). Data: 2026-09-27., [9] Local Cache. Local cache (previously fetched). Data: 2026-09-27., [10] Wikidata. wikidata. Data: 2026-09-27., [11] Literature. literature. Data: 2026-09-27., [12] Ustawa z 26.06.1974 r. — Kodeks pracy. Art.221–229. Dz.U. 2023 poz. 1465., [13] Rozp. MRiPS z 12.06.2018 r. — NDS/NDN. Dz.U. 2024 poz. 1017.
LiteratureDisposition of Hexahydrocannabinol Epimers and Their Metabolites in Biological Matrices following a Single Administration of Smoked Hexahydrocannabinol: A Preliminary Study, Pichini, Simona, Sprega, Giorgia, Simona Pichini et al., 2024, MDPI AG, 10.3390/ph17020249, 0, In 2023, hexahydrocannabinol (HHC) attracted the attention of international agencies due to its rapid spread in the illegal market. Although it was discovered in 1940, less is known about the pharmacology of its two naturally occurring epimers, 9(R)-HHC and 9(S)-HHC. Thus, we aimed to investigate th, 17, 0, 1, https://core.ac.uk/download/616532907.pdf, article, core, 6.38, open, Human metabolism of the semi-synthetic cannabinoids hexahydrocannabinol, hexahydrocannabiphorol and their acetates using hepatocytes and urine samples., et al., 2025, 10.1002/dta.3740, 38804224, 14, 1, https://europepmc.org/articles/PMC11922685?pdf=render, Hexahydrocannabinol (HHC), hexahydrocannabiphorol (HHCP) and their acetates, HHC-O and HHCP-O, respectively, are emerging in Europe as alternatives to tetrahydrocannabinol (THC). This study aimed to elucidate the metabolic pathways of the semi-synthetic cannabinoids HHC, HHCP, HHC-O and HHCP-O from , Europe PMC, 6.26, open, Identification and quantification of both isomers of hexahydrocannabinol, (9
<i>R</i>
)‐hexahydrocannabinol and (9
<i>S</i>
)‐hexahydrocannabinol, in three different matrices by mass spectrometry, Charline Bottinelli, Pauline Baradian, Amélie Poly et al., 2024, Rapid Communications in Mass Spectrometry, 10.1002/rcm.9711, 0, Context
Hexahydrocannabinol (HHC), a compound derived from synthetic production using cannabidiol (CBD) or delta‐9‐tetrahydrocannabinol (Δ
9
‐THC), has gained recent attention due to its presence in seized materia, 13, 0, 1, https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/rcm.9711, journal-article, crossref, 6.22, open, In vitro activation of the CB<sub>1</sub> receptor by the semi-synthetic cannabinoids hexahydrocannabinol (HHC), hexahydrocannabinol acetate (HHC-O) and hexahydrocannabiphorol (HHC-P)., et al., 2025, 10.1002/dta.3750, 38894658, 12, 1, https://europepmc.org/articles/PMC11994375?pdf=render, Semi-synthetic cannabinoids (SSCs) including hexahydrocannabinol (HHC) are emerging on the drug market and sold openly as purportedly legal replacements for cannabis and Δ<sup>9</sup>-THC. By the beginning of 2024, 24 European countries had identified HHC, often sold openly in edibles (foods/candy),, Europe PMC, 6.17, open, Studies Pertaining to the Emerging Cannabinoid Hexahydrocannabinol (HHC)., 2023, 10.1021/acschembio.3c00254, 37578929, 27, 1, https://europepmc.org/articles/PMC10510108?pdf=render, We report studies pertaining to two isomeric hexahydrocannabinols (HHCs), (<i>9R</i>)-HHC and (<i>9S</i>)-HHC, which are derivatives of the psychoactive cannabinoids Δ<sup>9</sup>- and Δ<sup>8</sup>-THC. HHCs have been known since the 1940s, but have become increasingly available to the public in th, Europe PMC, 6.17, open, Hexahydrocannabinol Pharmacology, Toxicology, and Analysis: The First Evidence for a Recent New Psychoactive Substance., et al., 2023, 10.2174/1570159x21666230623104624, 37357519, 24, 1, https://europepmc.org/articles/PMC10616920?pdf=render, <h4>Background</h4>During the last two years, hexahydrocannabinol (HHC), the hydrogenated derivative of tetrahydrocannabinol has been freely sold by internet websites as a "legal" replacement to THC and cannabis in a range of highly attractive branded and unbranded products, some of which are sold a, Europe PMC, 6.1, open, Quantitation of hexahydrocannabinol (HHC) and metabolites in blood from DUID cases., et al., 2024, 10.1093/jat/bkae030, 38581662, 9, 1, https://academic.oup.com/jat/advance-article-pdf/doi/10.1093/jat/bkae030/57176095/bkae030.pdf, Hexahydrocannabinol (HHC) was first reported in the EU in May 2022. HHC has three chiral carbon atoms, but only (6aR,9R,10aR)-HHC (9R-HHC) and (6aR,9S,10aR)-HHC (9S-HHC) have been encountered in HHC products. The aim of this study was to develop and validate a method for the quantitative analysis of, Europe PMC, 6, open, Identification of human hexahydrocannabinol metabolites in urine., Schirmer, Willi, Weinmann, Wolfgang, Kaudewitz, Julia et al., 2023, Sage, 10.1177/14690667231200139, 0, Hexahydrocannabinol (HHC) is a cannabinoid that has been known since 1940 but has only recently found its way into recreational use as a psychoactive drug. HHC has been used as a legal alternative to tetrahydrocannabinol (THC) in many countries, but first countries already placed it under their narc, 28, 0, article, core, 5.69, paywall, Preliminary pharmacokinetic and psychophysical investigations after controlled oral and inhalative consumption of hexahydrocannabinol (HHC)., et al., 2025, 10.1038/s41598-025-93931-4, 40128283, 4, 1, https://europepmc.org/articles/PMC11933371?pdf=render, The semi-synthetic cannabinoid hexahydrocannabinol (HHC) has become a highly discussed topic in forensic toxicology since 2022 due to its legal availability at this time and its psychoactive effects. This study aimed to investigate the pharmacokinetics, effects, and immunological detectability of HH, Europe PMC, 5.55, open, Hexahydrocannabinol and Hexahydrocannabiphorol Poisonings: Data From the Czech Toxicology Information Centre and Effects of Legislative Changes., et al., 2025, 10.1002/prp2.70162, 40855674, 3, 1, https://europepmc.org/articles/PMC12378148?pdf=render, Hexahydrocannabinol, a hydrogenated derivative of cannabinol, first came to the Czech Toxicological Information Centre (TIC) following reports of poisonings in May 2022. We conducted a retrospective observational study examining self-reported cases of hexahydrocannabinol and hexahydrocannabiphorol e, Europe PMC, 5.4, open
Nist linkhttps://webbook.nist.gov/cgi/cbook.cgi?ID=946512-74-9
Chembl id
Wikidata qidQ124082984
Chemspider url
Substance typeunknown
Grok description
Cross validationDane zweryfikowane z 4 źródeł (cache, pubchem, wikidata, literature). Wykrytych konfliktów: 0.