The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2017<\/year><\/dates><electronic-resource-num>10.1111\/bph.13580<\/electronic-resource-num><urls><related-urls><url>https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/pdfdirect\/10.1111\/bph.13580<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>2<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><\/authors><\/contributors><titles><title>'Entourage' effects of N-palmitoylethanolamide and N-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2008<\/year><\/dates><electronic-resource-num>10.1038\/bjp.2008.324<\/electronic-resource-num><urls><related-urls><url>https:\/\/onlinelibrary.wiley.com\/doi\/pdfdirect\/10.1038\/bjp.2008.324<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>3<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in 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name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>6<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>The anti-inflammatory mediator palmitoylethanolamide enhances the levels of 2-arachidonoyl-glycerol and potentiates its actions at TRPV1 cation channels.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2016<\/year><\/dates><electronic-resource-num>10.1111\/bph.13084<\/electronic-resource-num><urls><related-urls><url>https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/pdfdirect\/10.1111\/bph.13084<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>7<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Activation and desensitization of TRPV1 channels in sensory neurons by the PPAR\u03b1 agonist palmitoylethanolamide.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2013<\/year><\/dates><electronic-resource-num>10.1111\/bph.12029<\/electronic-resource-num><urls><related-urls><url>https:\/\/onlinelibrary.wiley.com\/doi\/pdfdirect\/10.1111\/bph.12029<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>8<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Palmitoylethanolamide induces microglia changes associated with increased migration and phagocytic activity: involvement of the CB2 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Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Palmitoylethanolamide protects against the amyloid-\u03b225-35-induced learning and memory impairment in mice, an experimental model of Alzheimer disease.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2012<\/year><\/dates><electronic-resource-num>10.1038\/npp.2012.25<\/electronic-resource-num><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>11<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the 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cells.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2001<\/year><\/dates><electronic-resource-num>10.1042\/0264-6021:3580249<\/electronic-resource-num><urls><related-urls><url>https:\/\/portlandpress.com\/biochemj\/article-pdf\/358\/1\/249\/707362\/bj3580249.pdf<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>14<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Therapeutic effect of the endogenous fatty acid amide, palmitoylethanolamide, in rat acute inflammation: inhibition of nitric oxide and cyclo-oxygenase systems.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2002<\/year><\/dates><electronic-resource-num>10.1038\/sj.bjp.0704900<\/electronic-resource-num><urls><related-urls><url>https:\/\/onlinelibrary.wiley.com\/doi\/pdfdirect\/10.1038\/sj.bjp.0704900<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>15<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Neuroprotective activities of palmitoylethanolamide in an animal model of Parkinson's disease.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2012<\/year><\/dates><electronic-resource-num>10.1371\/journal.pone.0041880<\/electronic-resource-num><urls><related-urls><url>https:\/\/journals.plos.org\/plosone\/article\/file?id=10.1371\/journal.pone.0041880&type=printable<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>16<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic 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Arruda et al.<\/author><\/authors><\/contributors><titles><title>Hallmarks\u00a0of primary headache: part 1 \u2013 migraine<\/title><secondary-title>The Journal of Headache and Pain<\/secondary-title><\/titles><dates><year>2024<\/year><\/dates><electronic-resource-num>10.1186\/s10194-024-01889-x<\/electronic-resource-num><urls><related-urls><url>https:\/\/thejournalofheadacheandpain.biomedcentral.com\/counter\/pdf\/10.1186\/s10194-024-01889-x<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>18<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Palmitoylethanolamide improves colon inflammation through an enteric glia\/toll like receptor 4-dependent PPAR-\u03b1 activation.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2014<\/year><\/dates><electronic-resource-num>10.1136\/gutjnl-2013-305005<\/electronic-resource-num><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>19<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>Shui Jiang<\/author><author>Lynne\u2010Marie Postovit<\/author><author>Annamaria Cattaneo et al.<\/author><\/authors><\/contributors><titles><title>Epigenetic Modifications in Stress Response Genes Associated With Childhood Trauma<\/title><secondary-title>Frontiers in Psychiatry<\/secondary-title><\/titles><dates><year>2019<\/year><\/dates><electronic-resource-num>10.3389\/fpsyt.2019.00808<\/electronic-resource-num><urls><related-urls><url>https:\/\/www.frontiersin.org\/articles\/10.3389\/fpsyt.2019.00808\/pdf<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>20<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>Evan C. Rosenberg<\/author><author>Richard W. Tsien<\/author><author>Benjamin J. Whalley et al.<\/author><\/authors><\/contributors><titles><title>Cannabinoids and Epilepsy<\/title><secondary-title>Neurotherapeutics<\/secondary-title><\/titles><dates><year>2015<\/year><\/dates><electronic-resource-num>10.1007\/s13311-015-0375-5<\/electronic-resource-num><urls><related-urls><url>https:\/\/link.springer.com\/content\/pdf\/10.1007\/s13311-015-0375-5.pdf<\/url><\/related-urls><\/urls><\/record>\n<\/records><\/xml>\n"

"\n\nMolGod<\/database>MOL-GOD<\/source-app>1<\/rec-number>17<\/ref-type><\/authors><\/contributors>The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2017<\/year><\/dates><electronic-resource-num>10.1111\/bph.13580<\/electronic-resource-num><urls><related-urls><url>https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/pdfdirect\/10.1111\/bph.13580<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>2<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><\/authors><\/contributors><titles><title>'Entourage' effects of N-palmitoylethanolamide and N-oleoylethanolamide on vasorelaxation to anandamide occur through TRPV1 receptors.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2008<\/year><\/dates><electronic-resource-num>10.1038\/bjp.2008.324<\/electronic-resource-num><urls><related-urls><url>https:\/\/onlinelibrary.wiley.com\/doi\/pdfdirect\/10.1038\/bjp.2008.324<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>3<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2009<\/year><\/dates><electronic-resource-num>10.1073\/pnas.0907417106<\/electronic-resource-num><urls><related-urls><url>https:\/\/escholarship.org\/uc\/item\/9123v26t<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>4<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Palmitoylethanolamide, a naturally occurring lipid, is an orally effective intestinal anti-inflammatory agent.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2015<\/year><\/dates><electronic-resource-num>10.1111\/bph.12907<\/electronic-resource-num><urls><related-urls><url>https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/pdfdirect\/10.1111\/bph.12907<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>5<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><\/authors><\/contributors><titles><title>Palmitoylethanolamide for the treatment of pain: pharmacokinetics, safety and efficacy.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2016<\/year><\/dates><electronic-resource-num>10.1111\/bcp.13020<\/electronic-resource-num><urls><related-urls><url>https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/pdfdirect\/10.1111\/bcp.13020<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>6<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>The anti-inflammatory mediator palmitoylethanolamide enhances the levels of 2-arachidonoyl-glycerol and potentiates its actions at TRPV1 cation channels.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2016<\/year><\/dates><electronic-resource-num>10.1111\/bph.13084<\/electronic-resource-num><urls><related-urls><url>https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/pdfdirect\/10.1111\/bph.13084<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>7<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Activation and desensitization of TRPV1 channels in sensory neurons by the PPAR\u03b1 agonist palmitoylethanolamide.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2013<\/year><\/dates><electronic-resource-num>10.1111\/bph.12029<\/electronic-resource-num><urls><related-urls><url>https:\/\/onlinelibrary.wiley.com\/doi\/pdfdirect\/10.1111\/bph.12029<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>8<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Palmitoylethanolamide induces microglia changes associated with increased migration and phagocytic activity: involvement of the CB2 receptor.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2017<\/year><\/dates><electronic-resource-num>10.1038\/s41598-017-00342-1<\/electronic-resource-num><urls><related-urls><url>https:\/\/europepmc.org\/articles\/PMC5428303?pdf=render<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>9<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Palmitoylethanolamide in CNS health and disease.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2014<\/year><\/dates><electronic-resource-num>10.1016\/j.phrs.2014.05.006<\/electronic-resource-num><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>10<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Palmitoylethanolamide protects against the amyloid-\u03b225-35-induced learning and memory impairment in mice, an experimental model of Alzheimer disease.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2012<\/year><\/dates><electronic-resource-num>10.1038\/npp.2012.25<\/electronic-resource-num><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>11<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2002<\/year><\/dates><electronic-resource-num>10.1038\/sj.bjp.0704466<\/electronic-resource-num><urls><related-urls><url>https:\/\/onlinelibrary.wiley.com\/doi\/pdfdirect\/10.1038\/sj.bjp.0704466<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>12<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Effects of homologues and analogues of palmitoylethanolamide upon the inactivation of the endocannabinoid anandamide.<\/title><secondary-title><\/secondary-title><\/titles><dates><year>2001<\/year><\/dates><electronic-resource-num>10.1038\/sj.bjp.0704199<\/electronic-resource-num><urls><related-urls><url>https:\/\/onlinelibrary.wiley.com\/doi\/pdfdirect\/10.1038\/sj.bjp.0704199<\/url><\/related-urls><\/urls><\/record>\n<record><database name=\"MolGod\">MolGod<\/database><source-app name=\"MOL-GOD\" version=\"3.1.4\">MOL-GOD<\/source-app><rec-number>13<\/rec-number><ref-type name=\"Journal Article\">17<\/ref-type><contributors><authors><author>et al.<\/author><\/authors><\/contributors><titles><title>Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer 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